Keywords: acid-resistant capsules, enteric capsules, enzyme sustained-release capsules, gut health capsules, US acid-resistant supplements, EU probiotics capsules
Core Overview (Quick Fact Sheet)
• Core Composition: HPMC (Hydroxypropyl Methylcellulose) or gelatin shell, FDA/EFSA-approved acid-resistant coating (shellac, pectin-based or HPMCAS), no artificial additives, preservatives or solvents—formulated to resist stomach acid without additional post-filling coatings.
• Key Specs: Acid resistance: Stable at pH 1-3 (stomach acid) for ≥2 hours; Dissolution: Targeted release at pH 6-7 (intestines); Sustained-release duration: 4-12 hours (customizable); Compliance: FDA, EFSA, NSF, FSSC 22000, Excipact certified; Moisture resistance: Low moisture level to accommodate hygroscopic ingredients.
• Physical Traits: Hard capsule structure, smooth surface, available in clear or opaque options; resistant to mechanical damage and temperature fluctuations; uniform thickness for consistent acid resistance; tasteless and odorless, capable of masking unpleasant tastes/odors of herbal or mineral ingredients.
• Standard Sizes: Available in sizes 000 to 5 (customizable), with size 1-3 as the most commonly used for probiotic and enzyme supplements; volume ranges from 0.28ml to 1.37ml to fit different formulation needs.
• Dietary Fit: 100% vegetarian (when HPMC-based), vegan, halal, kosher, non-GMO, gluten-free, allergen-free; BSE compliant; no animal-derived ingredients, suitable for diverse dietary preferences and cultural requirements in the US and EU markets.
1. What Are Acid-Resistant Capsules? & What Products Are They Suitable For?
Acid-resistant capsules are engineered with a special coating that resists stomach acid (pH 1-3) and dissolves in the intestines (pH 6-7), ensuring targeted delivery of probiotics and enzymes. This design solves a critical problem: most probiotics and enzymes are destroyed by stomach acid before reaching the gut, rendering them ineffective.
Acid-resistant capsules are most suitable for: probiotic supplements (all live-culture strains), digestive enzyme supplements (amylase, lipase, protease), gut health supplements, and any supplements that require targeted delivery to the intestines.
Optimized for the US and EU markets, ARSR capsules meet strict regulatory standards and align with growing consumer demand for effective gut health supplements.
2. Why Probiotics & Enzymes Need Acid-Resistant Capsules?
• Probiotics: Live cultures (e.g., Bifidobacterium, Lactobacillus) are acid-sensitive—AR capsules protect them from stomach acid, ensuring 90% of CFUs reach the intestines to support gut microbiome health.
• Enzymes: Digestive enzymes (e.g., amylase, lipase) are denatured by stomach acid; sustained-release coating ensures they activate in the intestines, improving nutrient absorption and reducing digestive discomfort.
• Sustained-Release Benefit: Delivers nutrients over 8-12 hours, maintaining consistent gut support—ideal for daily gut health regimens, a top 2026 wellness trend.
3. Our Acid-Resistant Capsule Solution
We offer industry-leading AR capsules tailored for probiotic and enzyme supplements, designed for US and EU cross-border success. Our products include:
• FDA/EFSA-approved acid-resistant coating (shellac, pectin-based) that dissolves precisely in the intestines, with no premature breakdown.
• Customizable sustained-release rates (4-12 hours) to match your supplement’s needs, from daily probiotics to enzyme blends.
• Compatibility with all probiotic strains and digestive enzymes, with batch testing to ensure acid resistance and efficacy—critical for Amazon and EU retail compliance.
For probiotic and enzyme brands looking to dominate 2026 US and EU markets, our AR capsules deliver the protection and efficacy your customers need.
4. Sample & Formulation Consultation
• Official Website: www.eekpharma.com | Online sample application and acid-resistant capsules technical guide download.
• Global Email: kevin@eekpharma.com | 24h response for custom acid-resistant coating, sustained-release formula and HPMC/pullulan capsules inquiries.
• Free Sample: Single/double-chamber acid-resistant capsules (HPMC/pullulan capsules) available; free formulation guidance for probiotic, enzyme and gut health supplements.
• Bulk Production: Custom filling volume, acid-resistant coating and shell customization supported; short lead time for US/EU regional bulk orders.

